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Finding
Finding
improvement
Elderly MDD patients receiving continuation ECT plus medications had significantly higher physical component scores on the SF-36 over 6 months compared to those receiving medications alone, with a 7-point advantage at 24 weeks.
| Effect size | 7 point advantage (PCS) |
| CI | 95% CI 3.5-10.4 |
| Follow-up | 6 months |
| Comparator | Venlafaxine 225mg/day plus lithium (0.4-0.6 mEq/L) alone (PHARM arm) |
| Effect summary | improvement; 7 point advantage (PCS); CI: 95% CI 3.5-10.4 |
| Effect modifiers | [{"modifier": "age", "interaction_p": "", "direction": "amplifies", "stratum_details": "Age was statistically significantly associated with Physical Health Factor T-Score, PF, and RP subscores", "plain_language": "Age influenced physical quality of life scores, with physical functioning and role physical more affected in older participants", "annotation_notes": "Age interaction tested for significance per statistical analysis section. Age significantly associated with physical subscores but paper does not give explicit interaction p-value."}, {"modifier": "psychosis status", "interaction_p": "", "direction": "null", "stratum_details": "Treatment interactions for psychosis were tested for significance", "plain_language": "Whether the patient had psychotic features did not change how much benefit they got from continuation ECT", "annotation_notes": "Psychosis interaction tested per methods but paper does not report it as significant, implying null."}] |
Connected entities
Conditions
Populations
Source
PMC5742556
Effects of Continuation Electroconvulsive Therapy on Quality of Life in Elderly Depressed Patients: A Randomized Clinical Trial