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Finding adverse
The hyper-CVAD regimen was associated with myelosuppression-related complications as its predominant toxicity profile, distinct from the asparaginase-related toxicities seen with ABFM.
ComparatorABFM regimen (which had predominantly asparaginase-related toxicity instead)
Effect summaryadverse
Adverse eventsmyelosuppression-related complications 7%, 7 deaths

Connected entities

Interventions
Hyper-CVAD chemotherapy regimen
Conditions
Acute lymphoblastic leukemia
Outcomes
treatment-related adverse events
Populations
Adolescents

Source

PMC5558853
Final results of a single institution experience with a pediatric-based regimen, the augmented Berlin–Frankfurt–Münster, in adolescents and young adults with acute lymphoblastic leukemia, and comparison to the hyper-CVAD regimen
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