ExploreFinding
Finding decline
Early-weaned BAN girls had significantly reduced weight velocity (0.02 vs 0.05 g/kg/day) and length velocity (0.73 vs 1.55 cm/month) compared to matched breastfeeding community girls between 15 and 18 months of age.
Effect sizeWeight velocity: 0.02 g/kg/day (BAN girls) vs 0.05 g/kg/day (community girls), p<0.05; Length velocity: 0.73 cm/month (BAN girls) vs 1.55 cm/month (community girls), p<0.05
CIWeight velocity BAN girls: 95%CI 0.01, 0.03; community girls: 95%CI 0.03, 0.07. Length velocity BAN girls: 95%CI 0.40, 1.06; community girls: 95%CI 0.98, 2.12
Follow-up12 months
ComparatorAge-, gender-, and clinic-matched breastfeeding community girls (self-reported HIV-negative mothers)
Effect summarydecline; Weight velocity: 0.02 g/kg/day (BAN girls) vs 0.05 g/kg/day (community girls), p<0.05; Length velocity: 0.73 cm/month (BAN girls) vs 1.55 cm/month (community girls), p<0.05; CI: Weight velocity BAN girls: 95%CI 0.01, 0.03; community girls: 95%CI 0.03, 0.07. Length velocity BAN girls: 95%CI 0.40, 1.06; community girls: 95%CI 0.98, 2.12
Effect modifiers[{"modifier": "sex", "interaction_p": "p=0.076 (group-by-visit interaction)", "direction": "reverses", "stratum_details": "Girls: weight velocity 0.02 vs 0.05 g/kg/day (p<0.05); length velocity 0.73 vs 1.55 cm/month (p<0.05). Boys: weight velocity 0.02 vs 0.03 g/kg/day (NS); length velocity not significantly different.", "plain_language": "Early weaning harmed growth in girls but not in boys. Girls consumed less fat in their diet and families were 4 times more likely to buy milk products for boys.", "annotation_notes": "Authors hypothesize the sex difference may be due to differential feeding practices: families were 4x more likely to purchase milk for boys. Girls consumed 20% of calories from fat vs boys 24%."}]

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Source

PMC3787136
The Health of HIV-exposed Children after Early Weaning
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