ExploreFinding
Finding null
Despite significant decreases in sitting blood pressure (21-28 mmHg systolic reduction), antihypertensive therapy was not associated with increased orthostatic blood pressure declines or worsening of cerebral blood flow during standing in any of the three treatment groups.
Effect sizeNo increases in orthostatic BP declines in any group; no worsening of orthostatic BFV declines
Follow-up12 months
ComparatorThree-way comparison (candesartan vs lisinopril vs HCTZ); within-group pre/post comparison
Effect summarynull; No increases in orthostatic BP declines in any group; no worsening of orthostatic BFV declines

Connected entities

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Source

PMC3608194
Antihypertensive therapy and cerebral hemodynamics in Executive Mild Cognitive Impairment: results of a Pilot randomized clinical trial
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