Explore › Finding
Finding null
Bupropion was not protective against abstinence-associated increases in depressive symptoms among smokers with unipolar depressive disorders who entered the trial with low depressive symptoms and achieved abstinence.
Effect size50% (17/34) vs 62% (18/29), Chi2=0.923, p=0.34
Follow-up12 weeks
ComparatorPlacebo (among those who achieved abstinence and had low baseline HAM-D-6)
Effect summarynull; 50% (17/34) vs 62% (18/29), Chi2=0.923, p=0.34

Connected entities

Interventions
Bupropion-SR
Conditions
abstinence-associated depressive symptom worsening
Outcomes
Prevention of osteoporosis

Source

PMC3505846
A Controlled Trial of Bupropion Added to Nicotine Patch and Behavioral Therapy for Smoking Cessation in Adults with Unipolar Depressive Disorders
Read on PMC → · View in graph →