Explore › Finding
Finding decline
Pediatric APL patients with FLT3 mutations had lower 5-year overall survival (62%) compared to FLT3 wild-type patients (68%), with FLT3 mutation status identified as an independent prognostic factor for OS in multivariate analysis.
Effect size62% vs 68%
Follow-up5 years
ComparatorFLT3 wild-type (FLT3/WT) pediatric APL patients on CALGB C9710
Effect summarydecline; 62% vs 68%

Connected entities

Interventions
FLT3 mutation testing
Conditions
Pediatric acute epiglottitis and supraglottitis
Outcomes
5-year overall survival
Populations
Children

Source

PMC3368997
FLT3 Mutation Status is a Predictor of Early Death in Pediatric Acute Promyelocytic Leukemia: A Report From The Children's Oncology Group
Read on PMC → · View in graph →