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Finding improvement
When all 445 participants were collapsed regardless of treatment, early improvement in anxiety-psychic (p<0.001, r2=0.143), somatic-gastrointestinal (p<0.001, r2=0.106), and somatic-general (p<0.001, r2=0.104) items significantly predicted remission after Bonferroni correction, while anxiety-somatic (p=0.029) lost significance after correction.
Effect sizeanxiety-psychic: p<0.001, r2=0.143; somatic-GI: p<0.001, r2=0.106; somatic-general: p<0.001, r2=0.104
ComparatorNon-improvement in these items at week 1 within the overall sample
Effect summaryimprovement; anxiety-psychic: p<0.001, r2=0.143; somatic-GI: p<0.001, r2=0.106; somatic-general: p<0.001, r2=0.104

Connected entities

Interventions
Any Willing Provider Laws
Conditions
Major Depressive Disorder
Outcomes
Remission

Source

PMC3111899
Do early changes in the HAM-D-17 anxiety/somatization factor items affect treatment outcome among depressed outpatients? Comparison of two controlled trials of St John’s Wort (Hypericum Perforatum) versus an SSRI
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