does intensive blood pressure control reduce stroke risk?

Category: Atherosclerosis

📊 8 findings in 1 studies
Intervention Condition Outcome / Effect Source
📊 Intensive blood pressure control vs stan
vs Standard blood pressure contro
Hypertension
Frail Older Adults
Intensive blood pressure control targeting systolic BP <120 mmHg did not significantly reduce total
69 vs 78 strokes
— PMC8224947
3.33 years
📊 Intensive blood pressure control vs stan
vs Standard blood pressure contro
Stroke
Frail Older Adults
Intensive blood pressure control targeting systolic BP <120 mmHg did not significantly reduce total
69 vs 78 strokes
— PMC8224947
3.33 years
📊 Intensive blood pressure control vs stan
vs Standard blood pressure contro
elevated cardiovascular risk
Frail Older Adults
Intensive blood pressure control targeting systolic BP <120 mmHg did not significantly reduce total
69 vs 78 strokes
— PMC8224947
3.33 years
📊 Intensive blood pressure control vs stan
vs Standard blood pressure contro
Hypertension
Frail Older Adults
Intensive blood pressure control resulted in similar numbers of hemorrhagic and ischemic stroke subt
Hemorrhagic: 6 vs 7; LAA: 11 vs 13; CE:
— PMC8224947
3.33 years
📊 Intensive blood pressure control vs stan
vs Standard blood pressure contro
Stroke
Frail Older Adults
Intensive blood pressure control resulted in similar numbers of hemorrhagic and ischemic stroke subt
Hemorrhagic: 6 vs 7; LAA: 11 vs 13; CE:
— PMC8224947
3.33 years
📊 Intensive blood pressure control vs stan
vs Standard blood pressure contro
elevated cardiovascular risk
Frail Older Adults
Intensive blood pressure control resulted in similar numbers of hemorrhagic and ischemic stroke subt
Hemorrhagic: 6 vs 7; LAA: 11 vs 13; CE:
— PMC8224947
3.33 years
📊 Intensive blood pressure control vs stan
vs Standard blood pressure contro
Hypertension
Frail Older Adults
Among SPRINT participants without prior cardiovascular disease, fewer strokes occurred in the intens
43 vs 61 strokes (p=0.09)
— PMC8224947
📊 Intensive blood pressure control vs stan
vs Standard blood pressure contro
Stroke
Frail Older Adults
Among SPRINT participants without prior cardiovascular disease, fewer strokes occurred in the intens
43 vs 61 strokes (p=0.09)
— PMC8224947
Synopsis

Intensive blood pressure control targeting systolic BP <120 mmHg did not significantly reduce total stroke incidence compared to standard control, with 69 vs 78 strokes observed in one study. (PMC8224947) Similarly, among participants with elevated cardiovascular risk, intensive blood pressure control did not significantly reduce stroke incidence compared to standard control (69 vs 78 strokes). (PMC8224947) Analysis of stroke subtypes in the SPRINT trial showed similar numbers of hemorrhagic and ischemic strokes between intensive and standard blood pressure control groups (e.g., hemorrhagic: 6 vs 7; large artery atherosclerosis: 11 vs 13). (PMC8224947) Among SPRINT participants without prior cardiovascular disease, there were fewer strokes in the intensive BP control arm (43 vs 61 strokes), but this difference did not reach statistical significance (p=0.09). (PMC8224947)

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