Preeclampsia | Top 13 novel treatment findings

Pravastatin reduces preeclampsia risk

The pravastatin group showed a lower rate of preeclampsia (17.5% vs 35% in controls), lower rates of severe preeclampsia, HELLP syndrome, acute kidney injury, and severe hypertension. Additionally, neonates in the pravastatin group had higher birthweights, better Apgar scores, and lower rates of composite neonatal morbidity and NICU admissions.

Study published: 2021-06-21

COVID-19 mRNA vaccination reduces stillbirths and preterm births in pregnant women

Vaccinated women experienced significantly lower rates of stillbirth (0.2% vs 0.8%) and preterm birth (5.1% vs 9.2%) compared to unvaccinated women, along with a reduced incidence of congenital anomalies.

Study published: 2022-07-06

Magnesium sulfate reduces cerebral palsy risk in preterm infants.

The study found that MgSO uptake increased in all maternity units, with the NPP improving uptake significantly. Enhanced support did not further improve uptake but was associated with better teamwork and understanding among staff.

Study published: 2023-02-16

Long-acting PrEP preferred by women

75% of participants preferred long-acting injectable PrEP over oral PrEP, citing longer duration of effectiveness and safety during pregnancy and breastfeeding as key factors.

Study published: 2022-10-30

Intrauterine exposure to antihypertensive drugs improves gestational age in pregnant women with hypertension.

Higher levels of maternal protein targets for calcium channel blockers were associated with an increase in gestational age by 3.99 days per 10mmHg decrease in systolic blood pressure; little evidence of detrimental effects on birthweight from genetic perturbation of drug pathways.

Study published: 2023-11-06

Diet and exercise improve outcomes for pregnant women with gestational diabetes

The study found that pregnant women diagnosed with GDM had a higher gestational age at diagnosis in the third trimester and a preference for cesarean sections. Effective management of GDM can lead to improved maternal and fetal health outcomes.

Study published: 2022-12-13

Pre-conception interventions help women maintain healthy BMI to reduce pregnancy risks.

Maintaining a healthy pre-conception BMI may reduce the risk of adverse pregnancy outcomes and complications for both mother and baby.

Study published: 2022-07-24

Sleep disturbances do not affect glycemia

The study found that sleep disturbance frequency was not associated with maternal glycemia or gestational diabetes subtypes, indicating no positive outcomes related to sleep disturbances in this context.

Study published: 2023-04-26

Encouraging fish and omega-3 intake improves fetal development in pregnant individuals

Increased intake of omega-3 fatty acids is associated with improved neurodevelopmental outcomes in offspring and reduced risk of preterm birth.

Study published: 2023-11-18

Interventions improve birth preparedness and reduce maternal mortality in Nigerian women

The study found that the pooled prevalence of good birth preparedness and complication readiness was 58.7%, with an increase in awareness and preparedness among women over recent years. More than half of the women had knowledge of obstetric danger signs, arranged for transportation, and saved money for childbirth.

Study published: 2021-11-03

Psychosocial interventions reduce anxiety, depression

The interventions led to a significant reduction in anxiety (d= -0.35) and depression (d= -0.37). Spiritual care education significantly reduced postpartum stress disorder (d= -62.00).

Study published: 2022-01-13

Education improves pregnancy outcomes for women with cardiometabolic risks.

Increased educational attainment is associated with improved pregnancy outcomes, including higher birth weight and lower odds of adverse outcomes such as ectopic pregnancy, hyperemesis gravidarum, gestational diabetes, preeclampsia, and preterm birth.

Study published: 2023-07-08

Holistic antenatal care improves outcomes

Holistic ANC has been shown to lower maternal anxiety levels, improve the quality of care received, and enhance overall health outcomes for both mothers and newborns.

Study published: 2024-05-01