Hypertension | Top 36 novel treatment findings

Intensive systolic blood pressure lowering reduces left ventricular hypertrophy risk in older patients with hypertension.

Intensive treatment was associated with a lower risk of new LVH (hazard ratio 0.83) and greater regression of mean left ventricular mass index (LVMI) by 0.38 g/m per year. The favorable effect on cardiovascular outcomes was also noted (HR 0.73).

Study published: 2024-03-27

Low diastolic blood pressure increases cardiovascular risk

The study found that isolated low diastolic blood pressure (ILDBP) was associated with a 1.32-fold increased risk of major adverse cardiovascular events (MACE) compared to normal diastolic blood pressure. In contrast, isolated diastolic hypertension (IDH) did not show a significant increase in MACE risk. The meta-analysis also indicated an increased MACE risk in patients with ILDBP.

Study published: 2023-08-16

Intensive blood pressure control reduces dementia risk in hypertensive patients

Patients with higher TyG levels had a lower risk of probable dementia, indicating a potential protective effect against cognitive decline in hypertensive individuals.

Study published: 2023-11-08

Gene-DASH diet interaction lowers blood pressure in hypertensive individuals.

The study found that individuals with certain genetic variants showed a significant interaction with the DASH diet score, leading to lower systolic blood pressure. Specifically, the interaction effect size was 0.42±0.09 mm Hg in the CHARGE cohort and 0.20±0.06 mm Hg in the UK Biobank cohort, indicating a beneficial effect of the DASH diet in genetically predisposed individuals.

Study published: 2023-11-11

Maintaining optimal blood pressure reduces all-cause mortality in older adults.

Participants with optimal blood pressure levels had a significantly lower risk of all-cause mortality (HR=0.265) and cardiovascular disease mortality (HR=0.274), especially in those aged 65 years and older.

Study published: 2024-05-31

Women veterans achieve better blood pressure control

After one year, 59% of men and 65% of women achieved blood pressure control, with women showing a 72% greater odds of maintaining control compared to men over five years.

Study published: 2024-04-23

Bluetooth-enabled Self Measured Blood Pressure monitoring improves hypertension control among marginalized patients.

Positive outcomes include improved patient engagement in managing hypertension, better communication between patients and healthcare providers, and potential reductions in blood pressure levels among participants.

Study published: 2023-08-23

Antihypertensive medication reduces blood-brain barrier leakage in patients with hypertension.

Increased blood pressure correlates with decreased blood-brain barrier integrity, but effective antihypertensive treatment is associated with reduced BBB leakage, suggesting a protective effect on brain health.

Study published: 2024-01-04

Intensive blood pressure management reduces high systolic blood pressure in patients with acute ischemic stroke.

A non-significant trend towards fewer high SBP protocol violations was noted, with similar rates of sICH and 3-month functional independence (mRS 0-2) between the two groups.

Study published: 2023-04-25

Community health workers improve blood pressure control in slum residents

At the end of the two-year follow-up, the proportion of individuals with optimally controlled blood pressure increased from 26% to 38%, indicating a significant improvement in hypertension management.

Study published: 2022-07-25

Mindfulness training boosts DASH diet adherence

The MB-BP program significantly increased interoceptive awareness (MAIA score increased by 0.54) and improved DASH diet adherence (DASH score increased by 0.62) among participants with poor adherence at baseline after 6 months.

Study published: 2023-05-15

Mindfulness reduces hypertension and stress

Participants showed a notable reduction in both systolic and diastolic blood pressure, along with significant improvements in stress levels compared to control groups.

Study published: 2023-12-08

Monitoring systolic blood pressure improves longevity in older women.

Women with SBP levels consistently maintained between 110 and 130 mmHg had a significantly higher probability of surviving to age 90, with a 31% absolute survival probability for those on medication and maintaining this range for 80% of the first 5 years of follow-up.

Study published: 2023-06-29

Motivational interviewing improves hypertension management

The study found a significant improvement in lifestyle modifications among the intervention group, with blood pressure control increasing from 24% at baseline to 48% post-intervention, indicating effective management of hypertension through motivational interviewing.

Study published: 2024-04-19

GLP-1 receptor agonists lower blood pressure

GLP-1RAs modestly reduced systolic blood pressure (SBP) compared to placebo, with significant reductions noted for semaglutide, liraglutide, dulaglutide, and exenatide. Only exenatide showed a significant reduction in diastolic blood pressure (DBP).

Study published: 2024-01-30

Amlodipine and Telmisartan lower blood pressure in Indian adults with hypertension.

The study reported that 70% of patients in Punjab and 76% in Maharashtra achieved controlled blood pressure at the first step of treatment. Overall, there was a significant mean decrease in systolic blood pressure by 16 mmHg in Punjab and 15 mmHg in Maharashtra.

Study published: 2023-08-21

Antihypertensive medications improve blood pressure control in hypertensive patients.

The study found that 72.5% of participants adhered to antihypertensive medications, but only 23.4% achieved controlled blood pressure. Male sex and home blood pressure measurement were predictors of better control.

Study published: 2024-01-12

Slow breathing lowers blood pressure

Significant reductions in systolic blood pressure (SBP) by 2.4 mmHg and diastolic blood pressure (DBP) by 1.6 mmHg were observed after 12 weeks of slow breathing exercises. Participants with higher baseline blood pressure experienced even greater reductions.

Study published: 2022-08-31

Acupuncture stabilizes blood pressure during surgery

The study aims to demonstrate that acupuncture can significantly reduce the differences between the highest and lowest mean blood pressures during surgery, leading to improved hemodynamic stability and reduced incidence of hypotension and hypertension.

Study published: 2024-07-26

Antihypertensive drugs lower blood pressure in older adults with hypertension.

The study found that antihypertensive drugs effectively lowered blood pressure, with significant reductions in systolic and diastolic BP compared to less intense treatment and placebo. The reductions were consistent across various baseline BP values, ages, and clinical characteristics.

Study published: 2021-02-23

Adhering to the Mediterranean diet lowers pregnancy cardiometabolic risks for women.

Higher adherence to the Mediterranean diet was associated with lower cardiometabolic risk scores at both 16 and 34 gestational weeks, indicating better health outcomes for both mother and child.

Study published: 2022-09-20

Mobile health interventions lower blood pressure in African Americans.

Some mHealth interventions demonstrated a significant reduction in blood pressure among vulnerable groups, particularly those that incorporated care teams, indicating potential effectiveness in improving hypertension control.

Study published: 2023-04-10

Blood pressure self-monitoring improves hypertension management in urban patients.

The study found that urban residence, comorbidity, regular healthcare visits, advice on monitoring devices, and knowledge of hypertension self-care were positively associated with blood pressure self-monitoring practice.

Study published: 2023-02-02

Sodium reduction lowers blood pressure

Significant reduction in blood pressure levels among hypertensive patients, with evidence supporting the effectiveness of sodium reduction as a strategy for blood pressure control.

Study published: 2023-09-18

Antihypertensive medications lower stroke recurrence risk in post-stroke patients

Effective management of hypertension can reduce the risk of stroke recurrence by 30% and improve patient outcomes post-stroke.

Study published: 2023-02-16

Digital app reduces hypertension effectively

Patients using the app experienced significant reductions in morning home systolic blood pressure, with a decrease of 4.7 mmHg at week 12 and 6.1 mmHg at week 24, which were greater than those observed in the historical control group.

Study published: 2024-03-04

Isometric exercise reduces blood pressure

Participants showed a consistent reduction in systolic blood pressure compared to baseline, with 87% adherence to the prescribed exercise intensity among those who completed the intervention.

Study published: 2024-02-18

Pharmacogenomic testing improves hypertension control

Significant improvements in blood pressure control were observed, with reductions in systolic blood pressure (SBP) by 14.8 mmHg and diastolic blood pressure (DBP) by 8.4 mmHg in patients with actionable genotypes. Overall, 58.2% of participants with uncontrolled hypertension had a DGI that reduced the efficacy of antihypertensive agents.

Study published: 2021-04-06

Monitoring heart rate improves outcomes in autonomic dysreflexia patients

Improved understanding of heart rate changes associated with autonomic dysreflexia, leading to better monitoring and management strategies during procedures that may trigger these episodes.

Study published: 2021-04-06

Gut metabolites reduce blood pressure

The study found a placebo-subtracted reduction in 24-hour systolic blood pressure of 6.1±9.9 mmHg. Day and night systolic blood pressure were reduced by 6.5±12.3 mmHg and 5.7±9.8 mmHg, respectively. Additionally, 24-hour central systolic blood pressure decreased by 7.2±14.7 mmHg. HAMSAB also significantly increased levels of acetate and butyrate by 7.8-fold.

Study published: 2022-06-22

Dietitian-led telehealth lowers blood pressure in obese adults with hypertension.

Both treatment arms showed a reduction in 24-hour systolic blood pressure, with the dietitian telehealth group demonstrating greater improvements in sleep systolic BP, sleep diastolic BP, and self-reported physical activity. The dietitian group also tended to have better weight loss and healthy eating index scores, although these were not statistically significant.

Study published: 2022-04-03

Lifestyle interventions improve cardiometabolic health in at-risk individuals.

Identification of modifiable lifestyle factors associated with improved cardiometabolic health, leading to potential interventions for disease prevention.

Study published: 2021-03-26

Metformin reduces blood pressure and hypertension

The study found that metformin use significantly reduced both systolic blood pressure (SBP) and diastolic blood pressure (DBP), as well as the risk of developing hypertension, particularly in two independent cohorts. The reduction in SBP was quantified at Beta=-1.05 (P <0.001) and DBP at Beta=-0.51 (P=0.096).

Study published: 2023-04-17

The Blood Pressure Postpartum Trial reduces cardiovascular risks in women with hypertensive disorders.

The trial aims to provide evidence on effective follow-up and lifestyle interventions that could potentially lower cardiovascular disease risks in postpartum women with a history of HDP.

Study published: 2023-04-25

Tobacco exposure increases arterial stiffness

The findings suggest that addressing tobacco exposure can improve vascular health outcomes, particularly in reducing elevated blood pressure and arterial stiffness in affected populations.

Study published: 2022-03-22

Blood pressure-lowering medications improve health outcomes in adults with hypertension

Improved adherence to blood pressure-lowering medications is associated with better blood pressure control, reduced risk of complications such as stroke and heart disease, and overall better health outcomes for individuals with hypertension.

Study published: 2024-05-29