The meta-analysis found a significant effect of NIBS in reducing anxiety and depression scores compared to the control condition, indicating that real stimulation can alleviate clinical symptoms in patients with anxiety disorders.
Significant reductions in anxiety, depression, and PTSD symptoms were observed, with effect sizes ranging from 0.75 to 0.86 at 3 months and sustained effects at 6 months. 50-75% of participants reported clinically meaningful improvements at 3 months.
Both 1 mA and 2 mA tDCS protocols significantly reduced fear and avoidance symptoms, worries, and improved emotion regulation and quality of life. The 2 mA protocol showed a greater improvement in avoidance symptoms and depressive states compared to the 1 mA group, and it also reduced attention bias to threat-related stimuli.
Significant reductions in anxiety scores compared to placebo were observed at multiple time points, with improvements in anxiety and depression symptoms correlating at subacute and sustained time points.
Positive outcomes included rapid and sustained reductions in depressive and anxiety symptoms, particularly with psilocybin and ayahuasca. MDMA showed some efficacy in reducing social anxiety symptoms, while LSD reduced anxiety in patients with life-threatening cancer.
Significant reductions in anxiety and depression scores were observed, with 45.7% reduction in GAD7 scores and 43.1% reduction in PHQ8 scores among patients with moderate symptoms at baseline.
Participants in the TMR group experienced reduced subjective anxiety during exposure tasks and showed a correlation between longer REM sleep and decreased anxiety levels. The study suggests that REM sleep contributes to the extinction process and emotional regulation.
The study found that task-based brain signal variability was a strong predictor of treatment outcomes, with a total predictive accuracy of .77. Patients showed significant reductions in social anxiety symptoms as measured by the LSAS-SR.
Participants reported significant reductions in anxiety symptoms, internalized prejudice, and depression symptoms, particularly those with lower coping self-efficacy. Bisexual and queer participants experienced greater reductions in internalized prejudice compared to their single gender-attracted peers.
Participants experienced medium to large reductions in both state and trait anxiety, which persisted for at least one week post-ceremony. Additionally, there were increases in mindfulness and decreases in neuroticism.
The treatment showed significant symptom reduction in participants with social anxiety. In RCT #1, the active group had a greater reduction in symptoms compared to the control group (-9.83 vs -4.13). In RCT #2, the active group also demonstrated a higher symptom reduction (-12.89 vs -7.48). Overall, the program was found to be safe, acceptable, and efficacious.
Stronger pre-treatment connectivity with specific brain regions predicted greater clinical improvement in patients undergoing CBT.
Identified six trajectory subgroups for both depression and anxiety, with some patients showing significant symptom improvement while others exhibited nonresponse; younger age and better overall health were linked to higher remission rates.
The primary positive outcomes expected from the intervention include increased participant satisfaction with the online therapy compared to generic wellbeing information and a significant reduction in psychological distress over time, as measured by standardized scales.
Patients reported high enjoyment levels (mean 8.2 out of 10) while using VR during procedures, and qualitative feedback indicated decreased anxiety and easier experiences during medical interventions.
Patients receiving mental health treatment were 87% less likely to be re-hospitalized, 73% less likely to have an emergency department visit, and 65% less likely to die from any cause compared to those who did not receive treatment.
The study found that models based on resting-state functional connectivity and structural MRI could predict treatment outcomes, with a mean absolute error of approximately 3.5 points, indicating some level of predictive validity for anxiety symptom reduction post-CBT.
A trend towards a decrease in mind wandering was observed across the four patients during the monaural beat stimulation condition compared to the control tone, indicating potential benefits in managing anxiety symptoms.
The intervention led to statistically significant reductions in clinically significant depressive and anxiety symptoms, as well as increases in COVID-19 protective behaviors among participants from baseline to post-intervention.
The findings indicate that higher CRP concentrations are associated with lower risks of depressive and anxiety symptoms, while higher IL-6 activity is linked to increased risk for depressive symptoms.
Individuals with affective disorders exhibited greater information-seeking behavior (directed exploration) in resting conditions, but this behavior was reduced by the anxiety induction. The study highlights the complex relationship between trait and state anxiety in decision-making processes.
The study found that individuals with the GG genotype of the TPH2 gene showed increased subjective anxiety and reduced vmPFC reactivity to threat-related stimuli during ATD, indicating a genetic vulnerability to anxiety under conditions of reduced serotonin signaling.
Psychological interventions were found to be effective in reducing symptoms of perinatal anxiety and comorbid anxiety and depression, with a medium post-treatment effect size. They were effective across various modalities, including online and group formats.
The study aims to demonstrate that telepsychiatry is not inferior to face-to-face treatment in terms of treatment effectiveness and patient satisfaction.
Positive outcomes include increased awareness of mental health issues, reduced stigma, and potential improvements in players' performance and well-being following discussions of their mental health struggles.
Adolescents showed significant engagement with the platform, with higher usage associated with reduced anxiety and depression symptoms. The study found that older adolescents and females logged in more frequently and accessed more resources, leading to better outcomes.
The helpline was effective in identifying and addressing the mental health needs of older adults, with a significant number reporting increased psychiatric symptoms during the pandemic.
Physiotherapists perceive a significant role in managing anxiety in patients with RRMS, leading to improved therapeutic relationships and potentially better rehabilitation outcomes. Enhanced communication and understanding of the MS journey are seen as facilitators in managing patient anxiety effectively.
Older adults who received two doses of the COVID-19 vaccine reported significantly lower levels of fear and anxiety related to COVID-19 compared to those who were not vaccinated.
The study found that loneliness is associated with altered emotional reactivity to social situations, suggesting that interventions for social anxiety may need to be adjusted for effectiveness in treating loneliness.
In vivo exposure resulted in significantly higher heart rate variability (HRV) levels, indicating a stronger activation of the parasympathetic nervous system compared to VR exposure, suggesting better therapeutic effects.
The interventions led to a significant reduction in anxiety (d= -0.35) and depression (d= -0.37) among participants. Spiritual care education notably reduced postpartum stress disorder (d= -62.00).
The findings suggest that women who engage in treatment for MaUD may experience better outcomes compared to men, including improvements in family relationships and medical issues.
Metformin users showed a significantly lower risk of developing dementia (before: 0.78, after: 0.88), anxiety disorders, and depression (before: 0.77, after: 0.71), as well as lower all-cause mortality (before: 0.69, after: 0.83) compared to sulphonylurea users.
Participants in the RNC group showed significantly lower levels of nicotine and toxicant exposure, reduced cigarette consumption, and a higher quit rate (18% vs. 4% for UNC) at the end of the follow-up period.
Early identification and intervention can significantly improve prognosis and reduce the risk of developing mood and anxiety disorders in adolescence.
The simulation predicts a median reduction of 4.17 cases of anxiety per 1,000 Multiracial individuals if ACE exposure is equalized with that of Whites, indicating a significant potential benefit from the intervention.
Positive outcomes include increased motivation to engage in environmental behaviors, improved mental health through community support, and a greater sense of empowerment and agency in addressing climate change. Participants may also experience reduced anxiety levels and enhanced emotional resilience.
The app showed high utilization during the first wave of the pandemic, with peaks following critical information releases, indicating its effectiveness in promoting emotional self-care.
The administration of Citalopram led to a reduction in the neural response to interoceptive sensations, particularly in anxious individuals, suggesting a potential therapeutic effect on anxiety-related interoceptive processing.